FAQ: What Are The Causes Of High Blood Levels Of Vitamin B12?

What happens if Vitamin B12 is high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

Should I be worried if my B12 is high?

Though daily high doses of B12 are unlikely to cause harm in most people, extremely high doses should be avoided unless prescribed by a healthcare professional. If you think you may be deficient in B12, speak with your doctor, who can recommend an appropriate treatment based on your level of deficiency.

Why would Vitamin B12 be high?

Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)

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Is B12 level of 1500 too high?

There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10.

What does high B12 mean in a blood test?

Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin.

How do I lower my B12 levels?

You can change your diet to include vitamin B12-fortified grains, a supplement or B12 injections, or a high-dose oral vitamin B12 if you are deficient. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12.

How long does it take to get rid of excess B12?

If a person stops consuming the vitamin, the body’s stores of this vitamin usually take about 3 to 5 years to exhaust. People should not take high doses of vitamin B12 as a cure-all, but otherwise the vitamin does not appear to be toxic; consuming excess amounts of B12 is not recommended.

What is a good B12 level?

The normal range for vitamin B12 can vary slightly depending on the lab. But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing.

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Can anemia cause high B12?

A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.

What causes high B12 and folate levels in blood?

However, if someone has a condition such as chronic myeloproliferative neoplasm, diabetes, heart failure, obesity, AIDS, or severe liver disease, then that person may have an increased vitamin B12 level. Ingesting estrogens, vitamin C or vitamin A can also cause high B12 levels.

What is normal level of vitamin B12 in elderly?

A serum vitamin B12 level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly. The laboratory diagnosis is usually based on low serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels.

Can fatty liver cause high B12 levels?

The levels of vitamin B12 were correlated with the stage of NAFLD, lipid profile and liver parameters. Results: Vitamin B12 levels were significantly lower in patients with NAFLD. Vitamin B12 levels inversely correlated with cholesterol and triglyceride levels.

Can you have high B12 levels and still be deficient?

However, a normal blood value cannot rule out a B12 deficiency, as has often been shown in scientific medical literature. Serum B12 can be false normal or even false high, while a deficiency is present.

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Does vitamin B12 lower blood sugar?

Type 2 diabetes as a metabolic syndrome may show improvement in glycaemic control with Vitamin B12 therapy as there is correction of hyperhomocysteinemia. In studies it is proved that combination of vit B12, folic acid and vit B6 are effective for hyperhomocysteinemia.

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