- 1 What is serum vitamin B12 test?
- 2 What is a normal serum vitamin B12 level?
- 3 Is B12 checked in routine blood work?
- 4 Why would serum B12 be elevated?
- 5 Why vitamin B12 test is done?
- 6 Should I be worried if my B12 is high?
- 7 Is 500 a good B12 level?
- 8 How do you know if your B12 is low?
- 9 What is normal level of vitamin B12 in elderly?
- 10 Is vitamin B12 tested in CBC?
- 11 Can you take too much B12?
- 12 Does CBC show vitamin B12 deficiency?
- 13 What does high B12 mean in blood test?
- 14 Is B12 level of 1500 too high?
- 15 Can fatty liver cause high B12 levels?
What is serum vitamin B12 test?
Overview: This test measures the amount of vitamin B12 present in the blood. Vitamin B12 plays an important role in the basic body functions that include maintaining brain health, producing blood cells and nerve functions.
What is a normal serum vitamin B12 level?
Understanding the Results
But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.
Is B12 checked in routine blood work?
This is why it’s important for your symptoms to be taken into account when a diagnosis is made. A particular drawback of testing vitamin B12 levels is that the current widely used blood test only measures the total amount of vitamin B12 in your blood.
Why would serum B12 be elevated?
Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)
Why vitamin B12 test is done?
Why It Is Done
A vitamin B12 test is used to: Check for vitamin B12 deficiency anemia. There are several risk factors for this anemia, such as those who have had stomach or intestinal surgery, small intestine problems, or people with a family history of this anemia.
Should I be worried if my B12 is high?
Though daily high doses of B12 are unlikely to cause harm in most people, extremely high doses should be avoided unless prescribed by a healthcare professional. If you think you may be deficient in B12, speak with your doctor, who can recommend an appropriate treatment based on your level of deficiency.
Is 500 a good B12 level?
The vitamin B12 standard reference range is 200–700 pg/ml whereas the proposed optimal range is 500–1300 pg/ml . Higher vitamin B12 ranges have been associated with increased cognitive function, and reflexes, decreased brain atrophy, confusion, weakness and depression .
How do you know if your B12 is low?
Symptoms of Vitamin B12 Deficiency
- Weakness, tiredness, or lightheadedness.
- Heart palpitations and shortness of breath.
- Pale skin.
- A smooth tongue.
- Constipation, diarrhea, loss of appetite, or gas.
- Nerve problems like numbness or tingling, muscle weakness, and problems walking.
- Vision loss.
What is normal level of vitamin B12 in elderly?
A serum vitamin B12 level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly. The laboratory diagnosis is usually based on low serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels.
Is vitamin B12 tested in CBC?
B12 and folate levels may be ordered when a complete blood count (CBC) and/or blood smear, done as part of a health checkup or an evaluation for anemia, shows a low red blood cell (RBC) count, decreased hemoglobin and hematocrit, and the presence of large RBCs.
Can you take too much B12?
Since B12 is a water-soluble vitamin, it’s generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population.
Does CBC show vitamin B12 deficiency?
Macrocytic/megaloblastic anemia and large red blood cells are associated with a vitamin B12 or folate deficiency and are often initially detected during a routine CBC.
What does high B12 mean in blood test?
Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin.
Is B12 level of 1500 too high?
There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10.
Can fatty liver cause high B12 levels?
The levels of vitamin B12 were correlated with the stage of NAFLD, lipid profile and liver parameters. Results: Vitamin B12 levels were significantly lower in patients with NAFLD. Vitamin B12 levels inversely correlated with cholesterol and triglyceride levels.