Quick Answer: Why A Patient With Partial Gastrectomy Need To Receive Intramuscular Vitamin B12?

Why do you have to give vitamin B12 injections to someone who has had some of their stomach removed?

Most people who have had a total gastrectomy, and some who have had a partial gastrectomy, need regular injections of vitamin B12 because this is difficult to absorb from food if your stomach has been removed.

What is necessary for the absorption of vitamin B12 from the intestines?

Vitamin B12 occurs in foods that come from animals. Normally, vitamin B12 is readily absorbed in the last part of the small intestine (ileum), which leads to the large intestine. However, to be absorbed, the vitamin must combine with intrinsic factor, a protein produced in the stomach.

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Does B12 deficiency affect muscles?

Over time, peripheral nerve damage resulting from vitamin B-12 deficiency can lead to movement problems. Numbness in the feet and limbs may make it hard for a person to walk without support. They may also experience muscle weakness and diminished reflexes.

Why does gastrectomy cause pernicious anemia?

Vitamin B12 malabsorption occurs when a protein known as intrinsic factor is either not produced by the stomach (this is a condition called pernicious anemia) or when the proximal stomach is resected (the portion of the stomach that produces intrinsic factor).

What blood problems would you expect to observe in a patient after total gastrectomy?

internal bleeding. blood clots. leaking from where the stomach has been closed. acid reflux – where stomach acid leaks back up into the oesophagus.

What is post gastric surgery syndrome?

Dumping syndrome is a condition that can develop after surgery to remove all or part of your stomach or after surgery to bypass your stomach to help you lose weight. The condition can also develop in people who have had esophageal surgery.

What is intrinsic factor and what is its relationship with vitamin B 12?

Intrinsic factor is a glycoprotein secreted by parietal (humans) or chief (rodents) cells of the gastric mucosa. In humans, it has an important role in the absorption of vitamin B12 (cobalamin) in the intestine, and failure to produce or utilize intrinsic factor results in the condition pernicious anemia.

Can B12 deficiency cause stomach issues?

Other symptoms of vitamin B12 deficiency involve the digestive tract. These symptoms include nausea (feeling sick to your stomach) and vomiting, heartburn, abdominal bloating and gas, constipation or diarrhea, loss of appetite, and weight loss. An enlarged liver is another symptom.

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Does B12 deficiency cause malabsorption?

enterocyte caused by severe vitamin B12deficiency, which is rapidly corrected by giving vitamin B12. Binding of intrinsic factor by intrinsic factor anti- bodies secreted into the gastric juice or bacterial overgrowth of the small bowel may contribute to the malabsorption in some patients.

How long does it take for nerves to heal from B12 deficiency?

Neurologic improvement begins within the first week also and is typically complete in 6 weeks to 3 months.

How do you know if your B12 is low?

Symptoms of Vitamin B12 Deficiency

  1. Weakness, tiredness, or lightheadedness.
  2. Heart palpitations and shortness of breath.
  3. Pale skin.
  4. A smooth tongue.
  5. Constipation, diarrhea, loss of appetite, or gas.
  6. Nerve problems like numbness or tingling, muscle weakness, and problems walking.
  7. Vision loss.

How long does it take to recover from B12 deficiency?

Recovery from vitamin B12 deficiency takes time and you may not experience any improvement during the first few months of treatment. Improvement may be gradual and may continue for up to six to 12 months.

Does pernicious anemia shorten your life?

Currently, early recognition and treatment of pernicious anemia provide a normal, and usually uncomplicated, lifespan. Delayed treatment permits progression of the anemia and neurologic complications. If patients are not treated early in the disease, neurological complications can become permanent.

Does pernicious anemia weaken your immune system?

Pernicious anaemia causes your immune system to attack the cells in your stomach that produce the intrinsic factor, which means your body is unable to absorb vitamin B12.

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What autoimmune disease causes pernicious anemia?

Pernicious anemia is sometimes seen in association with certain autoimmune endocrine diseases, such as type 1 diabetes, hypoparathyroidism, Addison’s disease, and Graves’ disease.

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