Readers ask: Why Am I Having Low B12 Symptoms Despite High Levels In Blood?

Can you have high B12 levels and still be deficient?

However, a normal blood value cannot rule out a B12 deficiency, as has often been shown in scientific medical literature. Serum B12 can be false normal or even false high, while a deficiency is present.

Can you have pernicious anemia with high B12 levels?

A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.

What autoimmune disease causes low B12?

Pernicious anaemia is the most common cause of vitamin B12 deficiency in the UK. Pernicious anaemia is an autoimmune condition that affects your stomach. An autoimmune condition means your immune system, the body’s natural defence system that protects against illness and infection, attacks your body’s healthy cells.

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What causes neurological symptoms with B12 deficiency?

A fatty substance called myelin is essential for the formation of these sheaths. Vitamin B12 plays a significant role in the synthesis and maintenance of myelin. The neurological problems caused by vitamin B12 deficiency later in life are due to the damage caused to the myelin sheath.

At what level should B12 be treated?

But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.

How long does B12 deficiency take to correct?

Recovery from vitamin B12 deficiency takes time and you may not experience any improvement during the first few months of treatment. Improvement may be gradual and may continue for up to six to 12 months.

What happens when your B12 levels are too high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

What causes elevated B12 levels?

Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)

What causes B12 levels to be high?

The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don’t worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.

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Is low B12 a sign of lupus?

Another autoimmune condition that can contribute to anemia is vitamin B12 deficiency. Pernicious anemia with antibodies to intrinsic factor resulting to impaired absorption of B12 may be present in patients before the diagnosis of SLE or appear after the diagnosis of SLE.

What happens when your vitamin B12 is low?

Not having enough B12 can lead to anemia, which means your body does not have enough red blood cells to do the job. This can make you feel weak and tired. Vitamin B12 deficiency can cause damage to your nerves and can affect memory and thinking.

What are the symptoms of low vitamin B12?

Symptoms of vitamin B12 deficiency

  • a pale yellow tinge to your skin.
  • a sore and red tongue (glossitis)
  • mouth ulcers.
  • pins and needles (paraesthesia)
  • changes in the way that you walk and move around.
  • disturbed vision.
  • irritability.
  • depression.

Can low B12 cause weight gain?

People with vitamin B12 deficiency are likely to experience a wide range of symptoms, though weight gain is unlikely one of them. If you’re experiencing unexplained weight gain, consider discussing it with your healthcare provider or a registered dietitian to determine the root cause.

Can a B12 deficiency cause dizziness?

Breathlessness and Dizziness

If you become anemic due to a B12 deficiency, you may feel short of breath and a bit dizzy, especially when you exert yourself. This is because your body lacks the red blood cells it needs to get enough oxygen to your body’s cells.

What causes vitamin B12 deficiency?

However, the most common cause of vitamin B-12 deficiency anemia is a lack of a substance called intrinsic factor, which can be caused when your immune system mistakenly attacks the stomach cells that produce this substance. This type of anemia is called pernicious anemia.

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