What Does High Levels Of B12 Mean?

What happens if your B12 is too high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

What causes high B12 levels?

The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don’t worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.

Is B12 level of 1500 too high?

There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10.

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How do I lower my vitamin B12?

As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).

Can Vitamin B12 damage your liver?

Some studies have indicated that elevated serum levels of vitamin B12 might be a sign of a serious and life-threatening disease. Such falsely high valued of serum vitamin B12 levels are observed in myeloproliferative disease, acute hepatitis, severe alcoholic liver disease, and cirrhosis.

What is a good B12 level?

The normal range for vitamin B12 can vary slightly depending on the lab. But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing.

What foods cause high B12 levels?

To increase the amount of vitamin B12 in your diet, eat more of foods that contain it, such as:

  • Beef, liver, and chicken.
  • Fish and shellfish such as trout, salmon, tuna fish, and clams.
  • Fortified breakfast cereal.
  • Low-fat milk, yogurt, and cheese.
  • Eggs.

What causes high B12 and folate levels in blood?

However, if someone has a condition such as chronic myeloproliferative neoplasm, diabetes, heart failure, obesity, AIDS, or severe liver disease, then that person may have an increased vitamin B12 level. Ingesting estrogens, vitamin C or vitamin A can also cause high B12 levels.

Can fatty liver cause high B12 levels?

The levels of vitamin B12 were correlated with the stage of NAFLD, lipid profile and liver parameters. Results: Vitamin B12 levels were significantly lower in patients with NAFLD. Vitamin B12 levels inversely correlated with cholesterol and triglyceride levels.

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How long does it take to get rid of excess B12?

If a person stops consuming the vitamin, the body’s stores of this vitamin usually take about 3 to 5 years to exhaust. People should not take high doses of vitamin B12 as a cure-all, but otherwise the vitamin does not appear to be toxic; consuming excess amounts of B12 is not recommended.

Can you have pernicious anemia with high B12 levels?

A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.

What medications can cause high B12 levels?

Medicines that can affect the test result include:

  • Colchicine.
  • Neomycin.
  • Para-aminosalicylic acid.
  • Phenytoin.

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